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Driving Directions to Jacksonville Florida: 2026 Navigation and Route Guide
"Disambiguation Note: Jacksonville, Florida spans over 840 square miles, making it the largest city by land area in the contiguous United States. Driving directions in Jacksonville generally target one of five major hubs: Downtown Jacksonville, Jacksonville International Airport (JAX), the Jacksonville Beaches, the Mayo Clinic campus, or the JAXPORT Cruise Terminal. Navigating into and around Jacksonville requires a clear understanding of its expansive highway system, major river crossings, and toll networks. As the northern gateway to Sunshine State travel along the Atlantic seaboard, Jacksonville is anchored by two major interstate corridors..."
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